Amendments to The First Schedule of The Misuse of Drugs Act

1. CNB has completed a review of the First Schedule of the Misuse of Drugs Act 1973 (“MDA”), to ensure that New Psychoactive Substances (NPS) and emerging cannabinol variants can be dealt with as controlled drugs under the MDA.

2. The following amendments will come into effect on 1 June 2024 (see Annex for details):

a) Listing of four NPS; and
b) Expanding the definition of ‘cannabinol derivatives’.

Global NPS Situation

3. The global NPS situation remains concerning. Novel NPS continue to surface every year. According to the United Nations Office on Drugs and Crime Early Warning Advisory on NPS, there were at least 1,230 substances reported from 141 countries and territories as of November 2023, an increase from 1,182 substances reported in the previous year.

4. NPS abuse has been linked to adverse health conditions, including paranoia, seizures, hallucinations and even death.

5. Listing the four novel NPS in the First Schedule will allow CNB to take enforcement action against those who traffic, possess, or consume these substances, or commit other offences under the MDA. CNB will continue to closely monitor the NPS situation and further respond as needed.

Cannabinol Derivatives

6. Cannabinol derivatives, such as tetrahydrocannabinol (THC), are compounds found in cannabis plants. CNB has noted the emergence of hexahydro derivatives, which are semi-synthetic cannabinoids that are reported to have the same harmful effects as THC. To allow us to take action against persons dealing in these new derivatives, we will expand the definition of ‘cannabinol derivatives’ in the MDA to cover them.

CENTRAL NARCOTICS BUREAU
31 May 2024

Annex

Additional Substances to be Listed in the First Schedule as Class A Controlled Drugs (with effect from 1 June 2024)

A. NPS

1. 2-(Ethylamino)-2-(2-fluorophenyl)-cyclohexanone (also known as 2-fluorodeschloro-N-ethyl-ketamine, 2-FDCNEK, 2-fluoro-2-oxo PCE or 2-fluoro NENDCK) and its fluoro positional isomers in the phenyl ring

2. N-Ethyl-1-(3-methoxyphenyl)-cyclohexanamine (also known as 3-Methoxyeticyclidine or 3-Methoxy-PCE or 3-MeO-PCE) and its methoxy positional isomers in the phenyl ring

3. N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1H-indazole-3-carboxamide (also known as ADB-INACA or ADMB-INACA) and its N-(1-amino-1-oxohexan-2-yl) isomers

4. 2-(1H-Indazole-3-carboxamido)-3,3-dimethylbutanoic acid and its hexanoic acid isomers

B. Definition of ‘Cannabinol Derivatives’

1. The inclusion of ‘or hexahydro derivatives’ to the meaning of ‘cannabinol derivatives’ at Part 4 of the First Schedule of the MDA.